8 Nootropics For Depression Guaranteed To Make You Feel Better

Depression is a mental health condition that affects about 7% of the world’s total population. The state of living and continuously demanding careers are the usual culprits why this statistics keep on ballooning. Psychologists and life coaches are the usual go-to answers to ask for help. Aside from their counseling, they also prescribe nootropics for depression to their patients.

These drugs target to increase the production of the feel-good hormones. We have to consider the fact that depression can be biological. This means that something has to be altered in the brain to ease the symptoms.

To help with your anxiety and depression, you can try taking some of these supplements. Remember that it’s best that you seek the opinion of your physician if you’re taking other medications.


1. Aniracetam

Of all the nootropics available nowadays, Aniracetam is so far the most popular choice for those want to target brain performance and reduction of depressive tendencies. Aniracetam is a fat-soluble nootropic that lifts up your mood and enhances your memory. But above all, it balances stress levels to avoid triggering anxiety attacks.

Some medical experts suggest that Aniracetam has the ability to balance the two hemispheres of the brain. However, this requires more proof. What’s for sure is that this nootropic can enhance the blood flow on the nervous system. It also keeps neurotransmitters healthy for better memory recall and retention.

Aniracetam has a calming effect, a little bit of a drowsy feeling may also take place.

2. Adrafinil

Adrafinil induces the wakefulness feeling and it makes you feel better with the production of dopamine and serotonin. Basically, these nootropics for depression targets to produce the Hypocretin neurotransmitter that enhances mental and physical energy. When it comes to alleviating the symptoms of depression, Adrafinil gives off a calming effect by reducing stress levels in the brain.

You can also observe better communication and focus when you take Adrafinil. However, one side effect could be the increase in sex drive. Some users find the smart drug to have the aphrodisiac effect as well as the tendency to have munchies.

nootropics for depression

3. N-Acetyl –Cysteine

N-Acetyl –Cysteine, abbreviated as NAC, is actually a treatment for HIV infection, cancer, and paracetamol overdose. But studies found that NAC can also stimulate the production of dopamine and other happy hormones that, in turn, relax the excitability tendencies of the nerves. It yields positive effects on the nervous system by working as an antioxidant and neuroprotector.

NAC is a form of amino acid, which explains why it’s an important nootropic for the brain. It’s a building block of protein that’s significant for the functionality of the brain’s neurotransmitter.

4. St. John’s Wort

As a traditional herb that’s been in use for decades, St. John’s Wort has gained various names like Klamath, rosin rose, and goat’s weed. This nootropics for depression is a long-time treatment for mood swings and open wounds. The mystical part is that St. John’s Wort was used as a means of driving evil spirits in the past.

According to medical trials and applications, St. John’s Wort has the ability to permeate the blood-brain barrier without the help of a reactive agent. It also targets to stop the firing neurons so the person won’t experience anxiety attacks. This herbal supplement is safe for kids and adults alike.

The bonus benefits are the anti-inflammatory and antibacterial properties.

nootropics for depression

5. Tianeptine

If most of the nootropics nowadays stimulate the production of happy hormones, Tianeptine works by arresting the overreactive neurons. This is a treatment for serious cases of anxiety and depression and it would likely require the prescription or guidance of a medical expert when administering.

Other findings for this drug are it can help delay neuro aging and in the future, it’s seen to be a powerful nootropic choice for memory boosting.

Before deciding to take this on your own, you have to know tar Tianeptine can establish tolerance. If not taken properly, the user can suffer from dependence.

6. L-Tryptophan

L-Tryptophan will convert into Tryptophan once it interacts with other substance in the body. Tryptophan is an amino acid that works by alleviating anxiety levels as well as appetite. What makes L-Tryptophan a very important nootropics for depression is that the decline of its supply level in the brain can cause massive mood crashes. The lack of it will also worsen insomnia.

One thing that you should know about L-Tryptophan is it’s a precursor of melatonin. This means that when you intake a supplement containing this substance, you’re helping your body regain its healthy sleeping habits.

nootropics for depression

7. Co-enzyme Q10

Even if a bit unknown in the nootropics world, the Co-enzyme Q10 is a powerful choice of the smart drug since it helps in cellular respiration, electron transport, and ATP production. All these are responsible for the 95% of our overall bodily energy. This drug is also called as ubiquinone, an oil-soluble substance.

If taken as an anti-depressive drug, it can reduce depression symptoms by 50% in just a month. It will also help in making dopamine function improve for at least 30%. It’s important to maintain a constant supply of ubiquinone in the body to avoid mood swings and brain fog.

8. Ginkgo biloba

Like Bacopa monnieri, Ginkgo biloba is a centuries-old herb used for a variety of health purposes. It actually makes a good job of reducing the mental and physical symptoms of depression. Users will have an easier time managing negative thoughts and social anxiety when they a Ginkgo biloba supplement.

One big thing that Ginkgo does is it prevents cerebrovascular issues that will directly trigger a depressive behavior. This herb contains chemicals called Terpene Lactones that help uplift a person’s mood.

Taking nootropics for depression can be your personal choice or a prescription from your doctor. Make sure that you’re not taking any medications or your current drug can be stacked with a nootropic. This way, you can avoid the adverse effects of an overdose.

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